SELECT 
  pfv.feature_id, 
  pfv.product_id, 
  pfv.variant_id, 
  gp.group_id 
FROM 
  cscart_product_features_values AS pfv 
  INNER JOIN cscart_product_variation_group_products AS gp ON pfv.product_id = gp.product_id 
  INNER JOIN cscart_product_variation_group_features AS gpf ON gpf.group_id = gp.group_id 
  AND gpf.feature_id = pfv.feature_id 
WHERE 
  pfv.lang_code = 'en' 
  AND gp.group_id IN (51, 49, 58)

Query time 0.00065

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "table_name": "gp",
      "access_type": "range",
      "possible_keys": ["PRIMARY", "idx_group_id"],
      "key": "idx_group_id",
      "key_length": "3",
      "used_key_parts": ["group_id"],
      "rows": 26,
      "filtered": 100,
      "index_condition": "gp.group_id in (51,49,58)"
    },
    "table": {
      "table_name": "gpf",
      "access_type": "ref",
      "possible_keys": ["PRIMARY", "idx_group_id"],
      "key": "idx_group_id",
      "key_length": "3",
      "used_key_parts": ["group_id"],
      "ref": ["herbaria_cscart_4_18.gp.group_id"],
      "rows": 1,
      "filtered": 100
    },
    "table": {
      "table_name": "pfv",
      "access_type": "ref",
      "possible_keys": [
        "PRIMARY",
        "fl",
        "lang_code",
        "product_id",
        "fpl",
        "idx_product_feature_variant_id"
      ],
      "key": "PRIMARY",
      "key_length": "6",
      "used_key_parts": ["feature_id", "product_id"],
      "ref": [
        "herbaria_cscart_4_18.gpf.feature_id",
        "herbaria_cscart_4_18.gp.product_id"
      ],
      "rows": 1,
      "filtered": 100,
      "attached_condition": "pfv.lang_code = 'en'",
      "using_index": true
    }
  }
}

Result

feature_id product_id variant_id group_id
69 339 6475 49
69 1565 6476 49
69 1566 6477 49
69 1567 6478 49
69 1568 6479 49
69 1569 6480 49
69 1570 6481 49
69 5556 7168 49
70 349 6512 51
70 1581 6507 51
70 1582 6508 51
70 1583 6509 51
70 1584 6510 51
70 1585 6511 51
70 1586 6506 51
70 1587 6513 51
78 376 6967 58
78 1612 6968 58
78 1613 6969 58
78 1614 6970 58
78 1615 6971 58
78 1616 6972 58
78 1617 6973 58
78 1618 6974 58
78 5476 7165 58